Endocrine Abstracts

Purpose: To analyze CT signs and parameters of vascularization of pulmonary neuroendocrine tumours (PNT) and their relationship with the development of ACTH ectopic syndrome.Materials and methods: 23 patients with PNT were evaluated with contrast-enhanced MDCT. Arterial and venous phases were obtained at 10 and 35 seconds after the attenuation of 200 HU at the descending aorta, a delayed phase was at 6–8 min after the start of injection of contrast...

Objective: To analyze long-term treatment outcomes and to determine prognostic factors affecting the survival of patients with ECS. Matherials and methods: Retrospective, observational study on 147 patients (88 women, 59 men) with ECS diagnosed between 1990 and 2021. Various imaging studies were performed on all patients to find the source of ACTH producing neuroendocrine tumor (NET). Multivariable analysis was performed using a Cox proportional hazards ...

BackgroundEctopic ACTH syndrome (EAS) is a rare cause of endogenous hypercortisolism.ObjectiveTo analyze clinical, biochemical features and treatment outcomes of patients with EAS.Materials and methodsRetrospective, observational study on 129 patients (79 women, 50 men) with EAS diagnosed between 1990 and 2020. Plasma levels of ACTH (reference range: morning 7.2&#...

Introduction: Recent studies have shown that microRNA could serve as biomarkers in various types of cancer and other diseases. Aim: To reveal microRNA that differ in patients with Cushing’s diseases (CD) and Ectopic ACTH-syndrome (EAS) to form a specific panel for differential diagnosis of ACTH-dependent Cushing’s syndrome (CS).Materials and Methods: Plasma samples from both sinuses and cubital vein were drained during in...